AL 8810 ethyl amide

AL 8810 ethyl amide

CAT N°: 10010470
Price:

134.00 113.90

AL 8810 is an 11?-fluoro analog of prostaglandin F2? (PGF2?) which acts as a potent and selective antagonist at the FP receptor.{7398} AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide. This modification is analogous to the PG N-ethyl amides, as typified by Bimatoprost, that have been introduced as alternative PG ocular hypotensive prodrugs.{8941} In contrast to AL 8810 which contracted the cat iris, AL 8810 ethyl amide showed no contraction activity at concentrations up to 10-4 M and did not antagonize the activity of PGF2?-ethanolamide in this system.{15015}

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