Adefovir dipivoxil

Adefovir dipivoxil

CAT N°: 28373
Price:

From 55.00 46.75

Adefovir dipivoxil is a prodrug form of the antiviral nucleoside analog adefovir (Item No. 18650).{45446} Adefovir dipivoxil inhibits hepatitis B virus (HBV) DNA synthesis in HepG2 2.2.15 cells infected with HBV (EC50 = 0.517 ?M).{45447} It is cytotoxic to HepG2 2.2.15 cells with a 50% cytotoxicity concentration (CC50) value of 540 ?M. Adefovir dipivoxil inhibits HBV replication in the liver of HBV transgenic mice (ED50 = 0.2 ?mol/kg per day).{45448} Formulations containing adefovir dipivoxil have been used in the treatment of chronic HBV infection.

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