Acetyl<wbr/>digitoxin

Acetyldigitoxin

CAT N°: 24024
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From 237.00 201.45

Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes.{41362} This inhibition results in loss of the transmembrane Na+ gradient, which decreases activity of the Na+/Ca2+ exchanger, increasing intracellular calcium levels, inotropy, and cardiac force.{29469,38192} Formulations containing acetyldigitoxin have been used for the treatment of heart failure and chronic atrial fibrillation.

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