€505.00 €429.25
Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38) (Item No. 24770).{41742} It binds to the PACAP receptor PAC1 (IC50 = 5.6 nM for the human receptor) and induces calcium mobilization and proliferation of PC12 cells (EC50s = 4.4 and 0.83 nM, respectively) with an efficacy comparable to PACAP (1-38). Acetyl PACAP (1-38) is resistant to degradation by dipeptidyl peptidase 4 (DPP-4) with a 10-fold longer half-life than PACAP (1-38), respectively.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 500 µg |
|---|---|
| Shipping | dry ice |
| Molecular formula | C205H333N63O54S • XCF3COOH |
| Smiles | NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(C=C1)O)NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](C)NC([C@H](C)NC([C@@H](NC([C@H](CC2=CC=C(C=C2)O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](C)NC([C@H](CCSC)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(C=C3)O)NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(C=C4)O)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@]([H])(NC([C@H](CC5=CC=CC=C5)NC([C@@]([H])(NC(CNC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC6=CN=CN6)NC(C)=O)=O)CO)=O)=O)=O)[C@@H](C)CC)=O)=O)[C@H](O)C)=O)=O)CO)=O)=O)CO)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)CCC(N)=O)=O)=O)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)=O)CC(C)C)=O)=O)=O)C(C)C)=O)CC(C)C)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CCCCN)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CCCCN)=O)CC(N)=O)=O)CCCCN)=O.FC(F)(C(O)=O)F |
| Molecular weight | 4576,3 |
| Formulation | A lyophilized powder |
| Purity | ≥95% |
| Custom code | 3504.00 |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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ISO/IEC 17025:2005
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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