Acetyl-6-formylpterin

Acetyl-6-formylpterin

CAT N°: 23303
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From 48.00 40.80

Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.{40442} It dose-dependently increases the surface expression of MHC-related 1 (Mr1) in WT3 cells overexpressing Mr1 (WT3-m) following incubation with E. coli but does not activate MAIT cells cocultured with WT3-m cells when used at concentrations ranging from 0.23-15 µM. Acetyl-6-formylpterin is also a degradation product of folic acid (Item No. 20515) and a precursor in the synthesis of 2’-hydroxy-7,8-dihydrofolate, which is a metabolite of para-aminosalicylic acid (PAS) in M. tuberculosis.{40441}

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