Acepromazine (maleate)

Acepromazine (maleate)

CAT N°: 27821
Price:

140.00 119.00

Acepromazine is a phenothiazine antipsychotic, analog of chlorpromazine (Item No. 16129), and a dopamine receptor antagonist.{46374} It also binds to muscarinic receptors in rat brain (IC50 = 350 nM) and inhibits contractions of guinea pig ileum induced by acetylcholine (Item No. 23829; IC50 = 840 nM).{46375} Acepromazine inhibits morphine-induced vomiting in dogs.{46376} It also inhibits development of a conditioned avoidance response, unconditioned escape response, and catalepsy in rats (ED50s = 0.98, 3.1, and 17 mg/kg, respectively).{46377} Formulations containing acepromazine have been used as tranquilizers and anesthetics premedicant in small and large animal veterinary care.

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