Acalabrutinib

Acalabrutinib

CAT N°: 19899
Price:

From 48.00 40.80

Acalabrutinib is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells.{32705} In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Item No. 16274) for inhibiting BTK and did not inhibit EGFR, Itk, or Txk signaling.{32705}

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