Ac-IETD-CHO (trifluoro<wbr/>acetate salt)

Ac-IETD-CHO (trifluoroacetate salt)

CAT N°: 27100
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From 122.00 103.70

Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM).{38794} It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 ?M.{46116} Ac-IETD-CHO (10 mg/kg) inhibits increases in hepatic caspase-3 activity, DNA fragmentation, cytosolic cytochrome c levels, and proteolytic processing of caspase-3, -8, and -9 proenzymes in a mouse model of Fas-induced apoptosis and liver failure.{46117}

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