AC-5216

AC-5216

CAT N°: 18522
Price:

From 51.00 43.35

AC-5216 is a high affinity agonist of the 18 kDa translocator protein (TSPO, previously called the peripheral benzodiazepine receptor) that exhibits a Ki value of 0.297 nM in rat whole brain and IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO.{29754} AC-5216 produces anxiolytic and antidepressant effects in various animal models, without inducing benzodiazepine-like adverse effects.{29754,29755}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide
  • Correlated keywords
    • AC5216 TSPO translocator protein peripheral benzodiazepine receptor XBD173 antidepressant anti-depressant anxiolytic
  • Product Overview:
    AC-5216 is a high affinity agonist of the 18 kDa translocator protein (TSPO, previously called the peripheral benzodiazepine receptor) that exhibits a Ki value of 0.297 nM in rat whole brain and IC50 values of 2.73 and 3.04 nM, respectively, against human and rat glial TSPO.{29754} AC-5216 produces anxiolytic and antidepressant effects in various animal models, without inducing benzodiazepine-like adverse effects.{29754,29755}

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