A-<wbr/>438079 (hydro<wbr>chloride)

A-438079 (hydrochloride)

CAT N°: 14580
Price:

From 134.00 113.90

A-438079 is a competitive antagonist of the nucleotide receptor P2X7 (pIC50 = 6.9).{22914} It inhibits both calcium flux and IL-1? release mediated by P2X7 while not affecting the activity of other P2X receptors.{22914,22913} A-438079 is effective in evaluating the role of P2X7 in nociception, oxidative stress, and apoptosis in cells and animals.{22915,22916,22917}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-[[5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl]methyl]-pyridine, monohydrochloride
  • Correlated keywords
    • 899507-36-9 receptors antagonists pains apoptosis oxidative stress neurosciences nucleotides P27 inhibits inhibitors inhibitions calcium flux animals cells A438079 A-438079 A 438079 HCl
  • Product Overview:
    A-438079 is a competitive antagonist of the nucleotide receptor P2X7 (pIC50 = 6.9).{22914} It inhibits both calcium flux and IL-1? release mediated by P2X7 while not affecting the activity of other P2X receptors.{22914,22913} A-438079 is effective in evaluating the role of P2X7 in nociception, oxidative stress, and apoptosis in cells and animals.{22915,22916,22917}

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