Virginiamycin M1

Virginiamycin M1

CAT N°: 9002172
Price:

From 524.00 445.40

Virginiamycin M1 is a macrolide antibiotic. It is a member of the streptogramin A group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin M1 acts synergistically with virginiamycin S1 to irreversibly inhibit protein synthesis in bacteria.{23008}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3R,4R,5E,10E,12E,14S)-8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
  • Correlated keywords
    • 1402-85-3 5365-57-1 11015-24-0 11031-71-3 12656-20-1 12739-05-8 191289-43-7 biochemical antibiotic infectious disease NSC244426 NSC87432 PA114A PA114A1 PA Factor M RP12536 Staphylomycin M1 StaphylomycinM1 Vernamycin A VernamycinA macrolide 50S ribosomal subunit peptidyl transferase center inhibit inhibitor initiation translocation bactericidal bactericide methicillin-resistant S. aureus Staphylococcus MRSA S1 irreversible irreversibly protein synthesis bacteria
  • Product Overview:
    Virginiamycin M1 is a macrolide antibiotic. It is a member of the streptogramin A group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin M1 acts synergistically with virginiamycin S1 to irreversibly inhibit protein synthesis in bacteria.{23008}

We also advise you