Lanicemine

Lanicemine

CAT N°: 9002129
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From 85.00 72.25

Lanicemine is a non-selective, voltage-dependent NMDA channel blocker (IC50 = 4-7 µM) that binds to sites within the channel pore with a Ki value of 0.56-2.1 µM.{27755} Compared to ketamine (Item No. 11630), lanicemine exhibits a lower propensity to be trapped within the NMDA channel (86% versus 54% trapping) following removal and reapplication of glutamate.{27755} It has been examined for its potential to produce antidepressant effects without adverse psychotomimetic activity.{27755,27756}

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