RSC-<wbr/>133

RSC-133

CAT N°: 9001839
Price:

From 55.00 46.75

RSC-133 is an indole compound that promotes the reprogramming of human somatic cells to pluripotent stem cells.{24835} Specifically, when used at 10 ?M with four standard reprogramming factors, it increases the number of human foreskin fibroblasts that express the stem cell marker alkaline phosphatase.{24835} RSC-133 induces pluripotency by both down-regulating inducers of cellular senescence and inhibiting DNA methyltransferase and histone deacetylase activities.{24835}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-[[(2E)-3-(1H-indol-3-yl)-1-oxo-2-propen-1-yl]amino]-benzamide
  • Correlated keywords
    • stems cells research epigenetics genes regulations regulates pluripotency somatic RSCs 133 RSC133 indoles reprogramming programming re-programming foreskin fibroblasts alkaline phosphatase DNA methyltransferase histones deacetylase
  • Product Overview:
    RSC-133 is an indole compound that promotes the reprogramming of human somatic cells to pluripotent stem cells.{24835} Specifically, when used at 10 ?M with four standard reprogramming factors, it increases the number of human foreskin fibroblasts that express the stem cell marker alkaline phosphatase.{24835} RSC-133 induces pluripotency by both down-regulating inducers of cellular senescence and inhibiting DNA methyltransferase and histone deacetylase activities.{24835}

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