Prostaglandin E<sub>1</sub> ethyl ester

Prostaglandin E1 ethyl ester

CAT N°: 9001730
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Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-?-linolenic acid.{5702} Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 value of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM.{960,1751} PGE1 is used to treat male erectile dysfunction and to maintain ductus arteriosus patency in infants.{3468,5876} PGE1 ethyl ester is an esterified form of the free acid which may be more amenable for certain applications.

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