5'-pGpG (sodium salt)

5′-pGpG (sodium salt)

CAT N°: 33889
Price:

322.00 273.70

5′-pGpG is a linearized form of cyclic di-GMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).{24607, 50984, 28201} It is a metabolite of cyclic di-GMP (Item No. 17144) formed via hydrolysis by various phosphodiesterases (PDEs) that binds to the cyclic di-GMP-I riboswitch with reduced affinity compared to cyclic di-GMP.{28201,54908} 5′-pGpG is intended for use as a negative control for cyclic di-GMP signaling.

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