PtdIns-<wbr/>(1,2-<wbr/>dihexanoyl) (sodium salt)

PtdIns-(1,2-dihexanoyl) (sodium salt)

CAT N°: 9000660
Price:

94.00 79.90

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(1,2-dihexanoyl) is a synthetic analog of natural PtdIns featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates IP3 and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

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