Oleoyl Serotonin

Oleoyl Serotonin

CAT N°: 9000629
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From 74.00 62.90

Oleoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Item No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} Oleoyl Serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 ?M) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 ?M).{18121}

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