17-<wbr/>oxo-<wbr/>7(Z),10(Z),13(Z),15(E),19(Z)-<wbr/>Docosapentaenoic Acid

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

CAT N°: 9000347
Price:

From 174.00 147.90

Docosapentaenoic acid (DPA) is a ?-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity.{16993,18161} It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPAR? agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).{18161}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 7Z,10Z,13Z,15E,19Z-17-oxo-docosapentaenoic acid
  • Correlated keywords
    • keto fatty acids DPA lipoxygenase oxidation ? aspirin COX-2 COX2 COX 2 anti-inflammatory antiinflammatory cardiovascular 17-keto-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
  • Product Overview:
    Docosapentaenoic acid (DPA) is a ?-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity.{16993,18161} It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPAR? agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).{18161}

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