CAY10398

CAY10398

CAT N°: 89740
Price:

From 31.00 26.35

CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 µM.{8714} Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA.{4011} However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide
  • Correlated keywords
    • reversible inhibitors histone deacetylase HD1 inhibits inhibitions CAY-10398 hdacs HDAC-1 HDACs HDAC 1 HDAC1 HDACIS 519054-34-3
  • Product Overview:
    CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 µM.{8714} Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA.{4011} However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC.

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