N-<wbr/>(4-<wbr/>acetamidophenyl)-<wbr/>Indomethacin amide

N-(4-acetamidophenyl)-Indomethacin amide

CAT N°: 70278
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From 26.00 22.10

N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively.{8243,8513} It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.

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