Farnesyl Pyrophosphate (ammonium salt)

Farnesyl Pyrophosphate (ammonium salt)

CAT N°: 63250
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102.00 86.70

Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols.{8343} It also serves as a donor in post-translational isoprenylation of proteins.{24323} FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 ?M), attenuating platelet aggregation.{24324} It has also been shown to regulate adipocyte function as an endogenous PPAR? agonist.{24326} Additionally, because of a flexible hydrocarbon chain that enables different conformations, FPP is a promiscuous ligand for a subset of nuclear receptors.{24325}

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