24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,{123,770} and by 15-LO in mammals.{4193} In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase.{3824} In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE (Catalog No. 38610), a compound which exhibits many biological activities.{4193} A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimulates EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation.{4902} Membrane-esterified 13(S)-HpODE has been identified in human atherosclerotic plaques.{2406}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 100 µg, 50 µg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 33964-75-9 |
| Molecular formula | C18H32O4 |
| Smiles | CCCCC[C@H](OO)/C=C/C=CCCCCCCCC(O)=O, CCCCC[C@H](OO)/C=C/C=CCCCCCCCC(O)=O, CCCCC[C@H](OO)/C=C/C=CCCCCCCCC(O)=O, CCCCC[C@H](OO)/C=C/C=CCCCCCCCC(O)=O |
| Molecular weight | 312,4 |
| Custom code | 2918.19 |
| Formulation | A solution in ethanol |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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