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9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on ?-linolenic acid.{2226} It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions.{6086,3824} 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.{6085,6087} The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.{6083,6084}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 100 µg, 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 111004-08-1 |
| Molecular formula | C18H30O4 |
| Smiles | CC/C=CC/C=CC=C[C@@H](OO)CCCCCCCC(O)=O, CC/C=CC/C=CC=C[C@@H](OO)CCCCCCCC(O)=O, CC/C=CC/C=CC=C[C@@H](OO)CCCCCCCC(O)=O |
| Molecular weight | 310,4 |
| Custom code | 2918.19 |
| Formulation | A solution in ethanol |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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