5-hydroxy Indole-3-acetic Acid-d<sub>6</sub>

5-hydroxy Indole-3-acetic Acid-d6

CAT N°: 37199
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5-hydroxy Indole-3-acetic acid-d6 (5-HIAA-d6) is intended for use as an internal standard for the quantification of 5-HIAA (Item No. 22889) by GC- or LC-MS. 5-HIAA is a metabolite of the monoamine neurotransmitter serotonin (5-HT; Item No. 14332).{40084} It is formed from serotonin via a 5-hydroxy indole-3-acetaldehyde intermediate by aldehyde dehydrogenase. 5-HIAA has been used as a biomarker for the detection of neuroendocrine tumors. Brain levels of 5-HIAA are decreased in patients with severe Alzheimer’s disease.{69100}

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