<sup>10</sup>Panx (trifluoroacetate salt)

10Panx (trifluoroacetate salt)

CAT N°: 36867
Price:

From 49.00 41.65

10Panx is a peptide mimetic of the pannexin 1 (PANX1) ectodomain and inhibitor of PANX1, an innexin family gap domain protein and component of membrane channels.{65334} It inhibits purinergic P2X7 receptor activation-induced dye uptake, constitutive dye uptake, and hemichannel currents, as well as ATP-induced caspase activation and IL-1? release in HEK293 cells when used at a concentration of 200 µM. 10Panx inhibits pannexin channel currents and connexin 46 channel currents in Xenopus oocytes expressing the human channels.{65335}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-?-aspartyl-L-seryl-L-tyrosine, trifluoroacetate salt
  • Correlated keywords
    • 955091-53-9 PANX-1 10-Panx IL1? HEK-293 P2X-7
  • Product Overview:
    10Panx is a peptide mimetic of the pannexin 1 (PANX1) ectodomain and inhibitor of PANX1, an innexin family gap domain protein and component of membrane channels.{65334} It inhibits purinergic P2X7 receptor activation-induced dye uptake, constitutive dye uptake, and hemichannel currents, as well as ATP-induced caspase activation and IL-1? release in HEK293 cells when used at a concentration of 200 µM. 10Panx inhibits pannexin channel currents and connexin 46 channel currents in Xenopus oocytes expressing the human channels.{65335}

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