Stercobilin (hydrochloride)

Stercobilin (hydrochloride)

CAT N°: 36509
Price:

From 116.00 98.60

Stercobilin is a fecal pigment and a metabolite of the heme catabolite bilirubin (Item No. 17161).{68032} It induces DNA damage in a comet assay in HepG2 cells when used at concentrations ranging from 0.5 to 17 µM.{68033} Stercobilin (20 and 30 µM) induces activation of NF-?B in a reporter assay and increases the expression of the genes encoding TNF-?, IL-1?, IL-6, inducible nitric oxide synthase (iNOS), and COX-2 in RAW 264.7 macrophages.{68034} Fecal and plasma levels of stercobilin are increased in ob/ob mice.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2R,3R,4S,16S,17R,18R)-3,18-diethyl-1,2,3,4,5,15,16,17,18,19,22,24-dodecahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid, hydrochloride
  • Correlated keywords
    • 531-13-5 11040-32-7 13671-96-0 13857-56-2 13857-57-3 20751-36-4 25021-22-1 30505-51-2 34786-57-7 47846-65-1 34217-90-8 13129-80-1 NF?B TNF? IL1? IL6 COX2 porcine bilirubin
  • Product Overview:
    Stercobilin is a fecal pigment and a metabolite of the heme catabolite bilirubin (Item No. 17161).{68032} It induces DNA damage in a comet assay in HepG2 cells when used at concentrations ranging from 0.5 to 17 µM.{68033} Stercobilin (20 and 30 µM) induces activation of NF-?B in a reporter assay and increases the expression of the genes encoding TNF-?, IL-1?, IL-6, inducible nitric oxide synthase (iNOS), and COX-2 in RAW 264.7 macrophages.{68034} Fecal and plasma levels of stercobilin are increased in ob/ob mice.

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