Fosinopril-d<sub>7</sub> (sodium salt)

Fosinopril-d7 (sodium salt)

CAT N°: 31917
Price:

670.00 569.50

Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril (Item No. 21899) by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor fosinoprilat.{39303} Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril (2.5 mg/kg) reduces fractional shortening and decreases left ventricular size in a porcine model of congestive heart failure.{39770} Formulations containing fosinopril have been used in the treatment of hypertension and congestive heart failure.

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