Norpropranol<wbr/>ol (hydro<wbr/>chloride)

Norpropranolol (hydrochloride)

CAT N°: 36011
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From 60.00 51.00

Norpropranolol is an active metabolite of the ?-adrenergic receptor (?-AR) antagonist propranolol (Item No. 23349).{54827,33933} It is formed from propranolol by the cytochrome P450 (CYP) isoform CYP1A2.{33933} Norpropranolol binds to ?-ARs (Kd = 42 nM in turkey erythrocytes) and inhibits (–)-isoproterenol-induced activation of adenylate cyclase with a Ki value of 175 nM.{54827}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-amino-3-(1-naphthalenyloxy)-2-propanol, monohydrochloride
  • Correlated keywords
    • 20862-11-7 64755-23-3 P-450 CYP-1A2
  • Product Overview:
    Norpropranolol is an active metabolite of the ?-adrenergic receptor (?-AR) antagonist propranolol (Item No. 23349).{54827,33933} It is formed from propranolol by the cytochrome P450 (CYP) isoform CYP1A2.{33933} Norpropranolol binds to ?-ARs (Kd = 42 nM in turkey erythrocytes) and inhibits (–)-isoproterenol-induced activation of adenylate cyclase with a Ki value of 175 nM.{54827}

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