Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
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€433.00 €368.05
Ganglioside GD1a is a sialic acid-containing glycosphingolipid that has been found in brain, erythrocytes, bone marrow, testis, spleen, and liver, as well as in serum lipoproteins.{54332,54333} It is shed into the tumor microenvironment from the surface of tumor cells, where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis.{25490} It functions as a toll-like receptor 2 (TLR2) co-receptor in isolated human monocytes, colocalizing with TLR2 and enhancing the binding of type IIb E. coli enterotoxin (LT-IIb-B5) to TLR2 when used at a concentration of 20 µM.{25484} Ganglioside GD1a (20 µM) increases VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs), as well as induces vascularization in a Matrigel™ plug assay in mice when used at a concentration of 20 µM/plug.{25490} It accumulates in the CNS of patients with galactosialidosis, a lysosomal storage disorder.{43703} This product contains ganglioside GD1a molecular species with primarily C18:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1062]
Territorial Availability: Available through Bertin Technologies only in France
| Size | 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 12707-58-3 |
| Molecular formula | C84H146N4O39 • 2NH4 (for stearoyl) |
| Smiles | OC[C@H]1O[C@@H](O[C@H]2[C@H](O[C@H]([C@@H]([C@H]2O[C@]3(C([O-])=O)C[C@@H]([C@H]([C@]([C@@H]([C@@H](CO)O)O)(O3)[H])NC(C)=O)O)O)O[C@H]4[C@@H]([C@H]([C@@H](O[C@@H]4CO)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC([R])=O)O)O)CO)[C@H](NC(C)=O)[C@@H](O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O[C@]6(C([O-])=O)C[C@@H]([C@H]([C@]([C@@H]([C@@H](CO)O)O)(O6)[H])NC(C)=O)O)O)CO)[C@H]1O.[NH4+].[NH4+] |
| Molecular weight | 1872,2 |
| Formulation | A solid |
| Purity | ≥98% |
| Custom code | 2938.90 |
| UNSPSC code | 12352100 |
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