Aminoethyl-<wbr/>SS-Propionic Acid

Aminoethyl-SS-Propionic Acid

CAT N°: 35501
Price:

From 82.00 69.70

Aminoethyl-SS-propionic acid is a cleavable disulfide linker.{66102,66103} It has been used in the synthesis of antibody-drug conjugates (ADCs) containing the antibody trastuzumab and a membrane-impermeable cytotoxin, which inhibits HER2 dimerization and induces cytotoxicity in HER2-positive breast cancer cells, respectively.{66103}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-[(2-aminoethyl)dithio]-propanoic acid
  • Correlated keywords
    • Amino-ethyl anti-body HER-2 AminoethylSS SSpropionic AminoethylSSpropionic
  • Product Overview:
    Aminoethyl-SS-propionic acid is a cleavable disulfide linker.{66102,66103} It has been used in the synthesis of antibody-drug conjugates (ADCs) containing the antibody trastuzumab and a membrane-impermeable cytotoxin, which inhibits HER2 dimerization and induces cytotoxicity in HER2-positive breast cancer cells, respectively.{66103}

We also advise you