(±)12(13)-EpOME MaxSpec^® Standard

Territorial Availability: Available through Bertin Technologies only in France

• Synonyms
  • (Z)-11-((2S,3R)-3-pentyloxiran-2-yl)undec-9-enoic acid
• Correlated keywords
  • (±)12(13)EpOME quantitative standard mass Max spec spectrometry lipidomics LC-MS LCMS CYP 2J2 2C8 2C9 1A1
• Product Overview:
  (±)12(13)-EpOME is the 12,13-cis epoxide form of linoleic acid (Item Nos. 90150 | 90150.1 | 21909).{651,59199} It is formed primarily via linoleic acid metabolism by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to (±)12(13)-EpOME production when pharmacologically induced.{59199} (±)12(13)-EpOME (500 µM) induces mitochondrial dysfunction and cell death in renal proximal tubule epithelial cells. (±)12(13)-EpOME MaxSpec® standard is a quantitative grade standard of (±)12(13)-EpOME (Item No. 52450) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)12(13)-EpOME MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.