Guanosine 5'-[?-thio]triphosphate (lithium salt)

Guanosine 5′-[?-thio]triphosphate (lithium salt)

CAT N°: 35098
Price:

From 72.00 61.20

Guanosine 5′-[?-thio]triphosphate (GTP?S) is a hydrolysis-resistant analog of GTP (Item No. 16060) that binds to and activates G proteins in the presence of magnesium.{61910} GTP?S has been used to obtain crystal structures of GTPases in their active states, as well as measure the stability of GTPases in the presence of ligands.{61911,30527} A radiolabeled form of GTP?S, [35S]GTP?S, is commonly used in binding assays to determine agonism or antagonism at G protein-coupled receptors (GPCRs).{61910,61912}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • guanosine 5?-(trihydrogen diphosphate), P?-anhydride with phosphorothioic acid, tetralithium salt
  • Correlated keywords
    • 37589-80-3 GTP?-S GTP-?S
  • Product Overview:
    Guanosine 5′-[?-thio]triphosphate (GTP?S) is a hydrolysis-resistant analog of GTP (Item No. 16060) that binds to and activates G proteins in the presence of magnesium.{61910} GTP?S has been used to obtain crystal structures of GTPases in their active states, as well as measure the stability of GTPases in the presence of ligands.{61911,30527} A radiolabeled form of GTP?S, [35S]GTP?S, is commonly used in binding assays to determine agonism or antagonism at G protein-coupled receptors (GPCRs).{61910,61912}

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