BRD3308

BRD3308

CAT N°: 34875
Price:

From 109.00 92.65

BRD3308 is an inhibitor of histone deacetylase 3 (HDAC3; Ki = 29 nM).{61709} It is selective for HDAC3 over HDAC1 and HDAC2 (Kis = 6,300 and 5,100 nM, respectively). BRD3308 (10 µM) reduces cytokine-induced increases in apoptosis in rat INS-1E ? cells. In vivo, BRD3308 (5 mg/kg) reduces plasma glucose levels in rats and increases plasma insulin levels in rats in a hyperglycemic clamp assay as a model of type 2 diabetes.{61710}

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