Caudatin

Caudatin

CAT N°: 34585
Price:

109.00 92.65

Caudatin is a C-21 steroid that has been found in C. auriculatum and has anticancer activity.{63178,63179} It is cytotoxic to SMMC-7721, MCF-7, and HeLa cells (IC50s = 24.95, 65.82, and 247.54 µM, respectively).{63178} Caudatin (50-300 µM) induces apoptosis in and inhibits mammosphere formation by MDA-MB-231 breast cancer cells, as well as decreases the number of cancer stem cells (CSCs) in the MDA-MB-231 cell population.{63179} In vivo, caudatin (10 mg/kg) reduces tumor volume in an MDA-MB-231 mouse xenograft model.

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