Ipidacrine

Ipidacrine

CAT N°: 34529
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From 92.00 78.20

Ipidacrine is an inhibitor of acetylcholinesterase (AChE; IC50 = 270 nM).{58245} It induces long-term potentiation (LTP) in rat hippocampal slices, an effect that can be blocked by the muscarinic antagonists atropine (Item No. 12008) or pirenzepine (Item No. 29527), when used at a concentration of 10 µM.{62325} Ipidacrine (0.03-1 mg/kg) prevents memory deficits induced by the anticholinergic agent scopolamine in the passive avoidance test in rats.{62325}

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