Antisauvagine-30 (trifluoro<wbr/>acetate salt)

Antisauvagine-30 (trifluoroacetate salt)

CAT N°: 34271
Price:

From 457.00 388.45

Antisauvagine-30 is a peptide antagonist of corticotropin-releasing factor receptor 2 (CRF2).{64043,64044} It is selective for CRF2? over CRF1 (Kis = 1.75 and 915 nM, respectively for the human receptors).{64043} Antisauvagine-30 (10 nM) inhibits sauvagine-induced cAMP production in HEK293 cells expressing mouse CRF2?.{64044} It prevents stress-induced contextual fear conditioning in mice.{64045} Antisauvagine-30 reduces vasoactive intestinal peptide-induced decreases in food intake in rats.{64046}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • D-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-methionyl-L-isoleucyl-L-?-glutamyl-L-isoleucyl-L-?-glutamyl-L-lysyl-L-glutaminyl-L-?-glutamyl-L-lysyl-L-?-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparaginyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-?-aspartyl-L-threonyl-L-isoleucinamide, trifluoroacetate salt
  • Correlated keywords
    • 220673-95-0 aSvg30 AS HEK 293
  • Product Overview:
    Antisauvagine-30 is a peptide antagonist of corticotropin-releasing factor receptor 2 (CRF2).{64043,64044} It is selective for CRF2? over CRF1 (Kis = 1.75 and 915 nM, respectively for the human receptors).{64043} Antisauvagine-30 (10 nM) inhibits sauvagine-induced cAMP production in HEK293 cells expressing mouse CRF2?.{64044} It prevents stress-induced contextual fear conditioning in mice.{64045} Antisauvagine-30 reduces vasoactive intestinal peptide-induced decreases in food intake in rats.{64046}

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