Urdamycin A

Urdamycin A

CAT N°: 29510
Price:

231.00 196.35

Urdamycin A is a bacterial metabolite originally isolated from S. fradiae that has antibacterial and anticancer activities.{53476,53477} It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis and strains of Arthrobacter and Streptomyces, but not the fungus S. cerevisiae, in a disc assay when used at a concentration of 1 mg/ml.{53477} Urdamycin A is cytotoxic to L1210 and HT-29, but not A549, cancer cells (IC50s = 7.5, 5, and >10 µg/ml, respectively).{53476}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3R,4aR,12bS)-9-[2,6-dideoxy-3-O-[(2S,5S,6S)-5-[(2,6-dideoxy-?-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-?-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8-trihydroxy-3-methyl-12b-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-benz[a]anthracene-1,7,12(2H)-trione
  • Correlated keywords
    • 104320-28-7 A32Y2 NSC372208 NSC606397 anti-bacterial cancer Bacillus Saccharomyces L-1210 HT29 A-549 Aquayamycin
  • Product Overview:
    Urdamycin A is a bacterial metabolite originally isolated from S. fradiae that has antibacterial and anticancer activities.{53476,53477} It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis and strains of Arthrobacter and Streptomyces, but not the fungus S. cerevisiae, in a disc assay when used at a concentration of 1 mg/ml.{53477} Urdamycin A is cytotoxic to L1210 and HT-29, but not A549, cancer cells (IC50s = 7.5, 5, and >10 µg/ml, respectively).{53476}

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