Chlorzoxazone-<wbr/>d<sub>3</sub>

Chlorzoxazone-d3

CAT N°: 34237
Price:

From 217.00 184.45

Chlorzoxazone-d3 is intended for use as an internal standard for the quantification of chlorzoxazone (Item No. 18869) by GC- or LC-MS. Chlorzoxazone is a centrally acting muscle relaxant and an activator of small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 µM for KCa2.2 and KCa3.1, respectively).{27789,23031} In vivo, chlorzoxazone (10 mg/kg) decreases alcohol, but not water, intake in a dose-dependent manner and reduces the propensity for rapid initial alcohol intake in rats with intermittent, but not continuous, access to alcohol.{43334} Formulations containing chlorzoxazone have been used in the treatment of pain and stiffness caused by muscle spasm.

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