Ogerin

Ogerin

CAT N°: 34228
Price:

From 54.00 45.90

Ogerin is a positive allosteric modulator of G protein-coupled receptor 68 (GPR68).{60501} It increases proton-induced cAMP production in HEK293T cells expressing the human receptor in a reporter assay. Ogerin inhibits proton-mediated calcium release in the same cells when used at a concentration of 10 µM. It impairs contextual, but not cued, fear conditioning in wild-type, but not Gpr68 knockout, mice when administered at a dose of 10 mg/kg.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[4-amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
  • Correlated keywords
    • GPR-68 HEK-293T 293-T ZINC-67740571
  • Product Overview:
    Ogerin is a positive allosteric modulator of G protein-coupled receptor 68 (GPR68).{60501} It increases proton-induced cAMP production in HEK293T cells expressing the human receptor in a reporter assay. Ogerin inhibits proton-mediated calcium release in the same cells when used at a concentration of 10 µM. It impairs contextual, but not cued, fear conditioning in wild-type, but not Gpr68 knockout, mice when administered at a dose of 10 mg/kg.

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