Escin Ib

Escin Ib

CAT N°: 33926
Price:

From 102.00 86.70

Escin Ib is a triterpene saponin that has been found in A. hippocastanum and has diverse biological activities.{60625,60627,60829,60828} It inhibits HIV-1 protease (IC50 = 50 µM).{60625} Escin Ib (50-200 mg/kg) inhibits carrageenan-induced paw edema in rats and scratching behavior induced by compound 48/80 (Item No. 22173) in mice.{60627} It inhibits ethanol absorption and increases glucose tolerance in rats.{60829} Escin 1b (10-50 mg/kg) also decreases mucosal lesion size and severity in a rat model of ethanol-induced gastric ulcers.{60828}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3?,4?,16?,21?,22?)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-?-D-glucopyranosyl-(1?2)-O-[?-D-glucopyranosyl-(1?4)]-?-D-glucopyranosiduronic acid
  • Correlated keywords
    • Aesculus HIV1
  • Product Overview:
    Escin Ib is a triterpene saponin that has been found in A. hippocastanum and has diverse biological activities.{60625,60627,60829,60828} It inhibits HIV-1 protease (IC50 = 50 µM).{60625} Escin Ib (50-200 mg/kg) inhibits carrageenan-induced paw edema in rats and scratching behavior induced by compound 48/80 (Item No. 22173) in mice.{60627} It inhibits ethanol absorption and increases glucose tolerance in rats.{60829} Escin 1b (10-50 mg/kg) also decreases mucosal lesion size and severity in a rat model of ethanol-induced gastric ulcers.{60828}

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