Alizapride-<sup>13</sup>C-d<sub>3</sub> (hydrochloride)

Alizapride-13C-d3 (hydrochloride)

CAT N°: 33471
Price:

From 182.00 154.70

Alizapride-13C-d3 is intended for use as an internal standard for the quantification of alizapride (Item No. 25645) by GC- or LC-MS. Alizapride is a dopamine D2 receptor antagonist (Ki = 66-340 nM in radioligand binding assays).{45087} It is selective for dopamine D2 over ?1-, ?2-, and ?-adrenergic receptors (IC50s = >10 µM for all). It reduces decreases in gastrointestinal transit induced by dopamine (Item No. 21992), apomorphine, or bromocriptine (Item No. 14598) in rats when administered at a dose of 5 mg/kg.{60588} Formulations containing alizapride have been used in the treatment of pre- and postoperative nausea.

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