Kuwanon C

Kuwanon C

CAT N°: 33421
Price:

55.00 46.75

Kuwanon C is a prenylated flavone originally isolated from M. alba that has diverse biological activities, including antioxidant, antibacterial, antiproliferative, and neuroprotective properties.{57492} It scavenges DPPH (Item No. 14805) radicals in a cell-free assay (EC50 = 72.99 µg/ml).{57493} It is active against E. coli, S. typhimurium, S. epidermis, and S. aureus (MICs = 10, 25, 6.25, and 6.25 µg/ml, respectively) and inhibits the growth of P388 mouse lymphoma cancer cells (IC50 = 14 µg/ml).{57494,57495} Kuwanon C (30 mg/kg) improves motor coordination in a rotarod test and decreases neuronal loss in the substantia nigra pars compacta in a mouse model of MPTP-induced Parkinson’s disease.{57496}

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