INNO-8875

INNO-8875

CAT N°: 33345
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From 55.00 46.75

INNO-8875 is an adenosine A1 receptor agonist.{59827,59826} It binds to adenosine A1 receptors (Ki = 0.97 nM) and is greater than 10,000-fold selective for adenosine A1 over A2 receptors. Topical application of INNO-8875 (25 µg/eye) reduces intraocular pressure in a rabbit model of ocular hypertension.{59826} INNO-8875 (1-50 µg/kg) decreases atrial refractoriness and heart rate, as well as slows atrioventricular nodal conduction, in anesthetized rats.{59827}

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