24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€234.00 €198.90
€234.00 €198.90
Bethanechol-d6 is intended for use as an internal standard for the quantification of bethanechol (Item No. 23830) by GC- or LC-MS. Bethanechol is an agonist of muscarinic acetylcholine receptors with IC50 values of 1,837, 25, 631, 317, and 393 µM for M1-5, respectively, in a radioligand binding assay using CHO cells expressing the human receptors.{40682} It inhibits M2-mediated increases in cyclic AMP induced by isoproterenol (Item No. 15592) in isolated guinea pig small intestine (IC50 = 127 µM).{18340} Bethanechol increases basal tone of isolated porcine intravesical ureter (EC50 = 4.27 µM).{27105} It also induces fluid secretion in the ileum, duodenum, and jejunum of anesthetized rats when administered at a dose of 60 µg/kg.{40787} Formulations containing bethanechol have been used to increase urination and improve smooth muscle tone in the gastrointestinal tract.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 500 µg |
|---|---|
| Shipping | dry ice |
| Molecular formula | C7H11D6N2O2 • Cl |
| Smiles | CC(OC(N)=O)C[N+](C([2H])([2H])[2H])(C)C([2H])([2H])[2H].[Cl-] |
| Molecular weight | 202,7 |
| Custom code | 3822.19 |
| Formulation | A solid |
| Purity | ≥99% deuterated forms (d1-d6) |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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