6,2',4'-Trimethoxyflavone

6,2′,4′-Trimethoxyflavone

CAT N°: 33150
Price:

From 109.00 92.65

6,2′,4′-Trimethoxyflavone is a flavonoid that has been found in T. acutifolius and has diverse biological activities.{58257,58258,58259} It acts as an antagonist of the aryl hydrocarbon receptor (AhR), inhibiting benzo[a]pyrene-induced AhR-dependent transcription in a reporter assay when used at concentrations of 2 and 10 µM.{58257} 6,2′,4′-Trimethoxyflavone decreases LPS-induced production of TNF-? in THP-1 cells (IC50 = 47.7 µg/ml).{58258} It inhibits cell migration and invasion, but not proliferation, of HN-30 head and neck squamous cell carcinoma (HNSCC) cells in vitro when used at a concentration of 10 µM.{58259}

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