HUHS015

HUHS015

CAT N°: 32915
Price:

From 102.00 86.70

HUHS015 is an inhibitor of prostate cancer antigen-1 (PCA-1; IC50 = 0.67 µM), also known as ?-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3).{57399} It inhibits proliferation of DU145 human prostate cancer cells by 54 and 81% in 2D dish and 3D agar assays, respectively when used at a concentration of 10 µM. HUHS015 (32 mg/kg) reduces tumor growth in a DU145 mouse xenograft model.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-1H-pyrazol-5-ol
  • Correlated keywords
    • HUHS-015 PCA1 ALKBH-3 ALKB H3 DU-145
  • Product Overview:
    HUHS015 is an inhibitor of prostate cancer antigen-1 (PCA-1; IC50 = 0.67 µM), also known as ?-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3).{57399} It inhibits proliferation of DU145 human prostate cancer cells by 54 and 81% in 2D dish and 3D agar assays, respectively when used at a concentration of 10 µM. HUHS015 (32 mg/kg) reduces tumor growth in a DU145 mouse xenograft model.

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