Ganglioside GD1b Polyclonal Antibody

CAT N°: 28642
Price:

767.00 651.95

Ganglioside GD1b (Item No. 19569) is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events.{31218} The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects.{31219} Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.{54530} Ganglioside GD1b Polyclonal Antibody can be used for ELISA and TLC immunoblotting applications. [Matreya, LLC. Catalog No. 1964]

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