Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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€835.00 €709.75
€835.00 €709.75
Ganglioside GM1 asialo (Item No. 15586) is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 (Item No. 19579) by neuraminidase.{25489,37774} Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody.{25488} The percentage of ganglioside GM1 asialo-positive natural killer (NK) and CD8+ T cells in the lung is increased in a mouse model of respiratory syncytial virus (RSV) infection compared with healthy animals.{25489} Depletion of ganglioside GM1 asialo-positive NK and T cells reduces IFN-? levels in the lung, reduces weight loss, and increases lung viral load in RSV-infected mice. Ganglioside GM1 Asialo Polyclonal Antibody can be used for ELISA and TLC immunoblotting. [Matreya, LLC. Catalog No. 1950]
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 µl |
|---|---|
| Shipping | dry ice |
| Molecular weight | 0 |
| Host | Rabbit |
| Antigen | Purified ganglioside GM1 asialo and complete Freund’s adjuvant |
| Isotype | IgG/IgM |
| Application(s) | ELISA, TLC immunoblotting |
| Formulation | 100 µl of polyclonal antibody to ganglioside GM1 asialo |
| Custom code | 3822.19 |
| UNSPSC code | 12352203 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
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