IL-4 Inhibitor

IL-4 Inhibitor

CAT N°: 32548
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From 92.00 78.20

IL-4 inhibitor is an inhibitor of IL-4.{54527} It binds to IL-4 with a Kd value of 1.8 ?M and inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 ?M). It is selective for IL-4 over IL-13 (EC50 = 18.2 ?M). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 ?M), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.

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