RO5028442

RO5028442

CAT N°: 31452
Price:

From 85.00 72.25

RO5028442 is a brain-penetrant antagonist of vasopressin V1a receptors (Kis = 1 and 39 nM for the human and mouse receptors, respectively).{58074} It is greater than 30,000-fold selective for V1 over V2 receptors, as well as over a panel of 120 receptors, ion channels, and enzymes at 3 µM.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • [6-chloro-1-[2-(dimethylamino)ethyl]-1H-indol-3-yl]spiro[isobenzofuran-1(3H),4?-piperidin]-1?-yl-methanone
  • Correlated keywords
    • RO 5028442 V 1A 1 2
  • Product Overview:
    RO5028442 is a brain-penetrant antagonist of vasopressin V1a receptors (Kis = 1 and 39 nM for the human and mouse receptors, respectively).{58074} It is greater than 30,000-fold selective for V1 over V2 receptors, as well as over a panel of 120 receptors, ion channels, and enzymes at 3 µM.

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